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Question #72644 (2010-04-26)

  i just found out my son may have sickle cell put what i
wont to know is how can he gt it if no one in my family have
it and no one on his father side of the family has it can
you help me with this question

Answer(s):

Hello, and thank you for consulting the Ask a Question service with your question about sickle cell anemia.

This service is staffed by librarians and we cannot give medical advice. I will try to provide you with some sites that can give you more information. However, the best source of information for health questions is your doctor or another health professional. Your local library may also be able to help you find more information.

The US National Library of Medicine has a page explaining about sickle cell disease:

http://ghr.nlm.nih.gov/condition=sicklecelldisease

This page includes the question, "How do people inherit sickle cell disease?"

"This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition."

This page from Genome.gov also explains how this disease is inherited:

http://www.genome.gov/10001219

Because it is caused by a recessive gene, both parents have to pass on the gene for sickle cell anemia, so it makes sense that a child could have it without any sign of it in their parents. I hope this answers your question.

This service exists to answer questions from and about Alberta, Canada. When time permits we do sometimes answer questions from elsewhere. To ensure fast service in the future, please consult this similar service in your own state:

http://www.michigan.gov/askalibrarian

They will be able to help you with any future questions. Thanks!